Generic Hydrea (Hydroxyurea)
Hydrea
Hydrea is used to treat certain types of cancer or sickled red blood cells.
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500 mg x 30 pills
$79.99
$2.67
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500 mg x 60 pills
$127.99
$2.13
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500 mg x 90 pills
$171.99
$1.91
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500 mg x 120 pills
$206.99
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500 mg x 240 pills
$372.99
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Product Description
Common use

Hydrea is used to treat certain types of cancer (melanoma, chronic myelocytic leukemia, cancer of the ovary, and primary skin cancer of the head and neck) or sickled red blood cells. Active ingredient of this drug is hydroxyurea. The exact mechanism of its action is unknown, it is supposed that it is cell cycle specific for the S phase of cell division, it interfere with synthesis of DNA, with no effect on synthesis of RNA or protein.



Dosage and direction

Take this potent medication exactly as prescribed. Drink plenty of water during treatment to assist your kidney to remove the drug from the blood and diminish side effects. The medicine may be taken with or without food. You may be advised by your doctor to poor the content of Hydrea capsule into a glass of water, if so mix it throughly and drink whole immediately. Do not touch or inhale the drug powder from the capsule. Even if such symptoms as nausea or vomiting appear, do not stop taking this medication. Contact your doctor if you are immediately vomiting after the dose. This drug may increase the risk of sickness and inflammation due to its effect on amount of blood cells which control immunity.



Precautions

Before to take Hydrea consult your doctor if you are being treated with radiation therapy or are currently on interferon (Actimmune, Betaseron, Roferon, Intron, Infergen, Alferon, Rebetron, Rebif). Notify your doctor about diseases you have and especially about poor bone marrow function, liver disease, or kidney disease.



Contraindications

Do not take Hydrea if you are allergic to the components of the drug. This medicine is contraindicated in the patients with bone marrow depression (leukopenia or thrombocytopenia). This medicine may be harmful to an unborn baby. Do not take Hydrea if you are pregnant or breastfeeding.



Possible side effect

Besides signs of allergic reaction such as facial swelling, skin rash and eruptions, hives, and pinpoint red spots on your skin Hydrea may cause skin ulcers, red patches, or darkened skin, symptoms of fever, flu, chills, white patches or sores inside your mouth or on your lips, body aches, nausea or vomiting, loss of appetite, diarrhea, easy bruising or bleeding, unusual weakness.



Drug interaction

Do not start or stop treatment with any medication without your doctor's permission. Inform your health care advisor about all drugs, health products, vitamins, minerals, and supplement substances you are currently taking and especially about anti-cancer drugs, didanosine, stavudine, to treat gout.



Missed dose

Never take a double dose of this medication. If it is almost time of the next dose just skip the missed portion and continue to take the medicine according to the schedule.



Overdose

Immediate medical help is needed if excessive amount of this drug was taken. Contact your doctor the soonest if somebody swallowed too much of Hydrea by chance or you suspect overdose. Symptoms of overdose are worsened side effects such as violet erythema, soreness, severe generalized hyperpigmentation of the skin, edema on palms and soles followed by scaling of hands and feet, and stomatitis.



Storage

Store Hydrea at room temperature between 20 and 25 C (68 and 77 F) away from moisture and heat.



Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

Accutane

Other names used:

  • Roaccutane®

Active Ingredients:

  • Isotretionin

How does Accutane work and what pharmaceutical group does it belong to?

Isotretionin the active ingredient of Accutane belongs to a group of drugs called retinoids, which are used mainly in treatment of skin disorders. The exact mechanism of Accutane is not currently known however it is clinically determined that the drug exerts dose-dependent suppressive effect on the sebaceous glands activity and decreases their size. The drug also expresses anti-inflammatory effect on skin as well as inhibits the formation of comedones. The effects of the drug are temporary however the acne remissions may be controlled.

Which conditions are treated with Isotretinoin?

The drug is indicated in treatment of:

  • Severe cystic acne vulgaris
  • Acne rosacea
  • Hidradenitis suppurativa

What should a patient know before using Accutane?

The Isotretinoin should not be used in cases of:

  • Known hypersensitivity to any components of the preparation or to other retinoids
  • Pregnancy
  • Liver or renal failure
  • Vitamin A hypervitaminosis
  • Severe hyperlipidemia

Tell your doctor about the following if any apply to you:

  • You have relatives with increased levels of lipids in blood and are predisposed to hyperlipidemia
  • You or your relatives suffer from diabetes
  • You are suffering from Alcoholism
  • You are treating a depression

Which adverse effects may manifest when using the medication?

The side effects of Accutane include:

  • Vitamin A hypervitaminosis manifested in the following: dry skin and mucous membranes, haemorrhage in the nasal cavity, hoarseness, conjunctivitis and etc.
  • Skin problems: rash, itching, facial dermatitis, sweatiness, hyperpigmentation, reversible allopecia and etc.
  • Locomotor system: muscle pain, joint pain, hyperostosis, tendonitis
  • CNS: behavior changes, depression, headache, increased intracranial pressure, seizures
  • Sensory organs: decreased vision acuity, photosensibilisation, cataract, decreased hearing , keratitis
  • Gastrointestinal tract: nausea, colitis, GI hemorrhage, rarely hepatitis.
  • Respiratory organs: bronchospasm
  • Haemopoietic system: decreased leukocyte and erythrocyte levels, increase or decrease of thrombocyte levels
  • Immune system: local or systemic infections caused be gram-positive bacteria
  • Other: Hematuria, pancreatitis, vasculitis, lymphadenopathy

It is not necessary that the side effects will manifest in an individual but the possibility still exist. For more information please consult your health care provider.

Which groups of drugs or specific preparations may interact with Isotretinoin?

The drug is affected by the following:

  • Vitamin A supplements
  • Corticosteroids
  • Tetracycline antibiotics
  • Epilepsy treatment
  • Oral contraceptives
  • St.John's worth

Tell your doctor about all the herbal preparations as well as prescription drugs that you are currently taking even if they are not on the list.

Important information for the patient: Accutane is supplied for individual use. Do not use it to treat other conditions not listed in the leaflet. Keep the product out of children reach. Do not reuse any disposable materials if supplied with the preparation.